Widespread PSA screening has led to an inordinate number of prostate biopsies being performed. The biopsy is an invasive procedure, fraught with potential complications. Preliminary studies suggest that semen cytology may provide an accurate and definitely less invasive diagnostic tool which might avoid subjecting the patient to biopsy. Ideally the cytologist could not only identify the tumor cells but, with the use of special staining techniques, also be able to ascertain the grade of the underlying tumor.
I would like to stimulate a more thorough study of this possibility in order to validate the use of semen cytology as an alternative to prostate biopsy.
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